1.个人信息(Personals)
女,1975.5.13,河南大学教授,理学博士,硕导,河南省优秀教师,河南省教育厅学术技术带头人,河南省高校青年骨干教师,中原食品实验室岗位科学家。Email:wjf@henu.edu.cn
2.受教育经历 (Educational Experience)
2009/09-2012/06,河南大学生命科学学院,理学博士
2005/09–2008/06,河南大学逆境生物学重点实验室,理学硕士
1993/09–1997/07,河南大学,本科
3.工作经历(Professional Experience)
2017/12–至今,河南大学,教授
2011/12-2017/12,河南大学,副教授
2008/08-2011/12,河南大学,讲师
1997/08-2005/07,开封高中,生物学教师(中级)
4.研究兴趣(Research Interests)
(1)药用植物学:将植物种质资源学科前沿研究和药物研发实践相结合,从化学成份、药理活性、分子机制等方面对我国部分药用植物进行研究。
(2)药用植物降血糖、抗肝损伤、抗菌领域:以抑制α-葡萄糖苷酶为靶点的中药活性成分追踪和降血糖作用机制研究,涉及葡萄糖的吸收和转运;以抗氧化活性为靶点的中药活性成分追踪和急性肝损伤作用机制研究;活性成分体内外抗菌机制研究,利用蛋白质组学等多组学技术,结合肠道微生态调控,研究植物化学成分对健康的影响。
5.承担项目情况(Financial Supports)
[1] 2021.01-2022.12,主持河南省科技攻关项目: MntC介导的白屈菜红碱抗金黄色葡萄球菌作用机制研究(212102310354),10万
[2] 2018.01-2019.12,主持河南省重点科技攻关项目(国际联合):藿香活性成分对葡萄糖转运吸收调控机制研究(182102410083),10万
[3] 2017.11-2018.12,参加保健食品原料目录研究专项课题研究:灵芝、灵芝孢子粉、枸杞子、螺旋藻(GXTC-1770075),145万
[4]2021.01-2022.12,主持河南省高等学校重点科研项目计划:白屈菜红碱抗金黄色葡萄球菌作用机制研究(21B360001)
[5] 2016.01-2017.12,参加河南省教育厅高校科技创新团队项目:药食两用资源应用开发(16IRTSTHN019),100万
[6] 2015.03-2016.10,主持河南省科技厅基础与前沿技术研究项目:离子液体-HPLC微量快速分析山高粱、茜草和赤芍活性成分方法研究(152300410064),5万
[7] 2014.01-2016.10,主持河南省科技厅基础前沿技术研究项目:藿香与广藿香活性物质基础比较分析(142300410123),3万
[8] 2013.02-2016.01,主持河南省科技厅基础前沿计划:珍珠菜保肝作用及对大鼠CYP3A4影响(132300410255)
[9] 2013.01-2015.12,主持河南省高等学校青年骨干教师资助计划项目(教高[2012]704号),2万
[10] 2012.01-2014.12,主持河南省科技厅科技攻关重点项目:珍珠菜和追风伞降血糖作用机制研究(122102310170)
[11] 2011.01-2013.12,主持河南省科技厅基础前沿计划项目:三种珍珠菜属植物降血糖活性成分研究(112300410075)
6.代表性论著(Publications)
期刊论文(Journal Articles)
[1] Jinfeng Wei, Baoguang Wang, Yixiao Chen, Qiuyi Wang, Adel F. Ahmed*, Yan Zhang* Wenyi Kang* The Immunomodulatory Effects of Active Ingredients From Nigella sativa in RAW264.7 Cells Through NF-κB/MAPK Signaling Pathways. Frontiers in Nutrition, 2022, 9, 1-16
[2] Jinfeng Wei, Baoguang Wang, Yixiao Chen, Qiuyi Wang, Adel F. Ahmed, Lili Cui , Xuefeng Xi, Wenyi Kang* Effects of two triterpenoids from Nigella sativa seeds on insulin resistance of 3T3-L1 adipocytes. Frontiers in Nutrition, 2022, 9, 1-12
[3] Changyang Ma, Xuebiao Wang, Wenjing Shao, Qingchun Zhao, Jinfeng Wei*, Zhenhua Liu*, Changqin Li*. Effects of a Cordyceps militaris With Herba epimedii Complex on Chronic Renal Failure Induced by Adenine in vivo. Natural Product Communications, 2022, 17(6): 1-7
[4] Yingying Zhao1, Jinfeng Wei1, Changqin Li, Adel F. Ahmedd, Zhenhua Liu*, Changyang M*A comprehensive review on mechanism of natural products against Staphylococcus aureus. Journal of Future Foods, 2022, 2(1): 25-33
[5] Lili Cui, Xianzhong Wang, Jie Lu, Jing Tian, Li Wang, Jiaojiao Qu, Zhenhua Liu, Jinfeng Wei*. Rapid Identification of Chemical Constituents in Artemisia argyiLe´vi. et Vant by UPLC-Q-Exactive-MS/MS. Journal of Food Quality, 2021,4: 1-7
[6] Lili Cui, Jinmei Wang, Mengke Wang, Baoguang Wang, Zhenhua Liu, Jinfeng Wei*, Wenyi Kang*. Chemical composition and glucose uptake effect on 3T3-L1 adipocytes of Ligustrum lucidum Ait. Flowers. Food Science and Human Wellness. 2020, 9: 124-129.
[7] Yingying Zhao, Dandan Xia, Panpan Ma, Xiaofeng Gao, Wenyi Kang,Jinfeng Wei*, Advances in the detection of virulence genes of Staphylococcus aureus originate from food. Food Science and Human Wellness 9 (2020) 40-44
[8] Juanjuan Zhang, Li Zhou, Lili Cui, Zhenhua Liu, Jinfeng Wei*, Wenyi Kang*, Antioxidant and -glucosidase inhibitiory activity of Cercis chinensis flowers. Food Science and Human Wellness. 9 (2020)313-319
[9] Adel F. Ahmed, Fatma A.K. Attia c,d, Zhenhua Liu, Changqin Li, Jinfeng Wei*, Wenyi Kang. Antioxidant activity and total phenolic content of essential oils and extracts of sweet basil (Ocimum basilicum L.) plants. Food Science and Human Wellness.2019
[10] Changyang Ma, Nan He, Yingying Zhao, Dandan Xia, Jinfeng Wei, Wenyi Kang. Antimicrobial Mechanism of Hydroquinone, Applied Biochemistry and Biotechnology,2019,1-13
[11] Lanting Xu#, Meimei Xing#; Xiaoqing Xu, Fatma SA Saadeldeen; Zhenhua Liu, Jinfeng Wei*, Wenyi Kang*, Alizarin increase glucose uptake through PI3K/Akt signaling and improve alloxan-induced diabetic mice, Future Medicinal Chemistry , 2019.1.17, 10: 1~12
[12] Pingyao Xie, Yong Zhang, Jinfeng Wei*, Wenyi Kang*. Antithrombotic effect and mechanism of Rubus spp. Blackberry. Food & Function, 2017:8:2000-2012 SCI Top 1区 2042-6496
[13] Jin-feng Wei, Zhi-juan Zhang, Lili Cui and Wen-yi Kang. Flavonoids in different parts of Lysimachia clethroides Duby Extracted by Ionic Liquid, Analysis by HPLC and antioxidant activity assay. Journal of Chemistry. 2017 SCI ISSN : 2090-9063
[14] Jinmei Wang, Pengli Lian, Qi Yu, Jinfeng Wei*, Wen yi Kang*. Purification, characterization and procoagulant activity of polysaccharides from Angelica dahurice roots. Chemistry Central Journal (2017) 11:17 SCI 三区ISSN:1752-153X
[15] Pengran Cao, Pingyao Xie, Xuebiao Wang, Jinmei Wang, Jinfeng Wei* Wen-yi Kang*. Chemical constituents and coagulation activity of Agastache rugosa. BMC Complementary and Alternative Medicine (2017) 17:93 SCI ISSN: 1472- 6882
[16] Jinmei Wang, Pengli Lian, Qi Yu, Jinfeng Wei*,Wenyi Kang*. Antithrombotic mechanism of polysaccharides in Blackberry (Rubus spp.) seeds. Food & Nutrition Research, 61:1, 1379862, DOI: 10.1080/16546628.2017.1379862 SCI二区 ISSN: 1654-6628 2017.10
[17] Zhi-Juan Zhang, Zhao-Yang Xia, Jin-Mei Wang, Jin-Feng Wei* ,Wen-Yi Kang,* Effects of Flavonoids in Lysimachia clethroides Duby on the Activities of Cytochrome P450 CYP2E1 and CYP3A4 in Rat Liver Microsomes. Molecules, 2016,6, 21(6)SCI三区 ISSN:1420-3049
[18]Jinfeng Wei, Pengran Cao, Jinmei Wang, Wenyi Kang. Analysis of tilianin and acacetin in Agastache rugosa by high-performance liquid chromatography with ionic liquids-ultrasound based extraction. Chemistry Central Journal. 2016,11, 10:76 SCI三区ISSN:1752-153X
[19] Jin-feng Wei, Zhen-hua Yin, Wen-yi Kang. VOLATILES OF LYSIMACHIA PARIDIFORMIS VAR. STENOPHYLLA, LYSIMACHIA FORTUMEI AND LYSIMACHIA CHIKUNGENSIS BY HS-SPME-GC-MS. Afr. J. Tradit. Complement Altern Med, 2014,7, 11(3), 70-75SCI ISSN:0189-6016
[20] Jin-feng Wei, Wen-yi Kang*. COMPOSITION OF THE VOLATILES OF Yucca gloriosa FLOWERS. Chemistry of Natural Compounds, 2013, 7, 49(3), 537-538 SCI ISSN:0009-3130
[21] Jin-feng Wei, Zhen-hua Yin,Wen-yi Kang*. VOLATILES FROM FLOWERS OF Photinia serrulata BY HS-SPME-GC-MS. Chemistry of Natural Compounds, 49(2): 354-355, 2013,5 SCI ISSN:0009-3130
[22] Jin-feng Wei, Hai-peng Gu, Wen-yi Kang*. ANALYSIS OF VOLATILES IN THE MALE FLOWER OF Ilex cornuta BY HS-SPME-GC-MS. Chemistry of Natural Compounds, 49(2):367-368, 2013,5 SCI ISSN:0009-3130
[23] Jin-feng Wei, Zhen-hua Yin, Wen-yi Kang*. Volatiles in flowers of Viburnum odoratissimum.. Chemistry of Natural Compounds, 2013,3 49(1): 154-155 SCI ISSN:0009-3130
[24] Jin-feng Wei, Zhen-hua Yin, Fu-de Shang*. Volatiles in the Lysimachia clethroides Duby by HS-SPME-GC-MS. African Journal of Pharmacy and Pharmacology. 6(33): 2484-2487, 2012,9 SCI ISSN:1996-0816
[25] Jin-feng Wei, Yuan-yuan Li, Zhen-hua Yin, Fang Gong Fu-de Shang*. Hepatoprotective effect of Lysimachia paridiformis Franch var. stenophylla Franch on CCl4-induced acute liver injury in mice. African Journal of Pharmacy and Pharmacology. 6(13): 956-960, 2012.4 SCI ISSN:1996-0816
[26] Jin-feng Wei, Yuan-yuan Li, Zhen-hua Yin, Fang Gong, Fu-de Shang*. Antioxidant activities in vitro and hepatoprotective effects of Lysimachia clethroides Duby on CCl4-induced acute liver injury in mice. African Journal of Pharmacy and Pharmacology. 6(10): 743-750, 2012,3 SCI ISSN:1996-0816
论著(Books)
[1] 魏金凤、陈岩、康文艺、王贵声、尹震花, 一种从光炭轮菌属真菌中提取色酮、萘酚类化合物的方法.2023, ZL 202210084108.8
[2] 刘振花、康文艺、魏金凤、马常阳、李昌勤、呼谧允、牛云, 烟花苷在月季花中的提取分离方法. 2022, ZL 2019 10327284.8
[3] 魏金凤、陈岩、康文艺、王贵声、尹震花, 一种抗炎化合物Dalditone A及其制备方法和应用. 2023, ZL 2022 1 0084314.9
[4] 康文艺、魏金凤、王金梅、崔丽丽、余琦,垂丝海棠提取物和活性化合物、制备方法及应用,2019,中国ZL201510987656.1
[5] 康文艺、魏金凤、朱晓娣、何楠、余琦,一种益智叶提取物及其制备方法、应用,2019,中国 CN201510425389.9
[6] 康文艺、魏金凤、尹震花、李园园、巩芳,珍珠菜提取物及其提取方法和应用,2013,中国ZL201110281698.5
[7] 康文艺、魏金凤、张伟、连朋丽、谢平耀,一种抗凝血黑莓籽多糖及其提取分离方法、应用,2017,中国ZL201510529023.6
[8] 康文艺、魏金凤、高林、冯晓、黄嬛、尹春霞、李园园、王钦玲,南湖菱壳的用途、降糖有效部位及该部位的提取方法,2012,中国 ZL201110008008.9
7.奖励(Awards)
[1] 魏金凤,Analysis of tilianin and acacetin in Agastache rugosa by high-performance liquid chromatography with ionic liquids-ultrasound based extraction河南省教育厅优秀科技成果,论文一等奖,2019
[2] 魏金凤,Volatiles in flowers of Viburnum odoratissimum河南省教育厅优秀科技成果,论文二等奖,2019
[3] 魏金凤,康文艺,Analysis of tilianin and acacetin in Agastache rugosa by high-performance liquid chromatography with ionic liquids-ultrasound based based extraction河南省第四届自然科学学术奖—论文奖一等奖,2018
[4] 魏金凤,露珠珍珠菜化学成分研究,河南省教育厅优秀科技成果,论文二等奖,2020
[5] 魏金凤,康文艺,COMPOSITION OF THE VOLATILES OF Yucca gloriosa FLOWERS,河南省教育厅优秀科技成果,论文二等奖,2020
[6] 魏金凤,ANALYSIS OF VOLATILES IN THE MALE FLOWER OF Ilex cornuta BY HS-SPME-GC-MS2018年度河南省教育厅优秀科技论文奖二等奖,2018
[7] 魏金凤,离子液体辅助萃取山高粱中4种黄酮类成分的研究2018年度河南省教育厅优秀科技论文奖二等奖,2018
[8]魏金凤 VOLATILES OF LYSIMACHIA PARIDIFORMIS VAR. STENOPHYLLA, LYSIMACHIA FORTUMEI AND LYSIMACHIA CHIKUNGENSIS BY HS-SPME-GC-MS2017年度河南省教育厅优秀科技论文二等奖2017
[9]魏金凤,VOLATILES FROM FLOWERS OF Photinia serrulata BY HS-SPME-GC-MS2017年度河南省教育厅优秀科技论文二等奖,2017
[10]魏金凤,Composition of the essential oil of Lysimachia paridiformis. Chemistry of Natural Compounds,”2013年河南省第二届自然科学学术奖-自然科学优秀学术论文二等奖,2013
[11]魏金凤,王俊霞,康文艺. 废电池浸出液对荆芥生理及挥发性成分含量的影响,河南省第二届自然科学学术奖-河南省自然科学优秀学术论文二等奖,2013
[12]魏金凤,Hepatoprotective effect of Lysimachia paridiformis Franch var. stenophylla Franch on CCl4-induced acute liver injury in mice,河南省教育厅科技成果奖一等奖,2015
[13]魏金凤,Antioxidant activities in vitro and hepatoprotective effects of Lysimachia clethroides Duby on CCl4-induced acute liver injury in mice,河南省教育厅科技成果一等奖,2015
[14]魏金凤,Jin-feng We. Volatiles in the Lysimachia clethroides Duby by head space solid phase microextraction couple,河南省教育厅科技成果奖二等奖,2016
[15]魏金凤,Jin-feng We.Antioxidant activities,a-glucosidase inhibitory in vitro and effects of Lysimachia paridiformis Franch.var.stenophylla Franch.on alloxan-induced diabetic mice in vivo.河南省教育厅科技成果奖二等奖,2016
[16]魏金凤,VOLATILES OF LYSIMACHIA PARIDIFORMIS VAR. STENOPHYLLA, LYSIMACHIA FORTUMEI AND LYSIMACHIA CHIKUNGENSIS BY HS-SPME–GC- MS 开封市第十一届自然科学优秀学术成果奖三等奖,2015
[17] 魏金凤,王俊霞,康文艺. NaCL胁迫下金叶过路黄生理及叶组织挥发性成分变化分析. 中国药学杂志. 开封市第十届自然科学优秀学术成果奖二等奖,2014
[18] 药用植物在肠道菌群、致病菌调控与质量控制应用,中国商业联合会科学技术奖,全国商业科技进步奖一等奖,2021.12,13(参加)
[19] 药食两用资源功效成分识别与质量控制关键技术 河南省科学技术进步奖二等奖, 2021.02,10(参加)
[20] 谱效关系结合敲除技术快速确定功效成分及功能产品开发. 中国商业联合会科学技术奖一等奖,2019.12,10(参加)