1.个人信息(Personals)
陈晓宇,女,Tel: 15996272892,Email:chenxiaoyu@njau.edu.cn
2.受教育经历 (Educational Experience)
2012.9-2016.6 安徽农业大学 食品科学与工程专业 工学学士
2016.9-2019.6 南京工业大学 食品科学专业 工学硕士
2019.9-2023.6 南京农业大学 食品科学与工程专业 工学博士
3.工作经历(Professional Experience)
2023.7-至今 河南大学,讲师,Journal of Future Foods青年编委。
4.研究兴趣(Research Interests)
(1)食药两用资源的活性成分提取、分离和鉴定。
(2)天然产物活性研究:天然活性成分的降血糖、抗炎等作用,以及其作用靶点和分子机制研究。
5.承担/参与项目情况
[1] 2023.08.16—2025.12.31,参与河南省重点研发专项项目—植物源食品功能配料精准营养研发关键技术及应用;
[2] 2020.01-2024.12,参与国家自然科学基金面上项目—瑞士乳杆菌素NX371广谱抗菌的分子机制研究。
6.代表性论著(Publications)
期刊论文(Journal Articles)
1. X Y Chen, H Y Zhao, Y J Lu, F Q Meng, Z X Lu*, Y J Lu*. Surfactin mitigates dextran sodium sulfate-induced colitis and behavioral disorders in mice by mediating gut-brain-axis balance. Journal of Agricultural and food Chemistry.2023,71 (3): 1577-1592. (IF=5.895,Q1/一区).
2. X Y Chen, H Y Zhao, F Q Meng, L B Zhou, Z X Lu*, Y J Lu*. Surfactin alleviated hyperglycaemia in mice with type 2 diabetes induced by a high-fat diet and streptozotocin. Food Science and Human Wellness. 2023,12(6): 2095-2110. (IF=8.022,Q1/一区).
3. X Y Chen, H Y Zhao, Y J Lu, H W Liu, F Q Meng, Z X Lu*, Y J Lu*. Surfactin mitigates a high-fat diet and streptozotocin-induced type 2 diabetes through improving pancreatic dysfunction and inhibiting inflammatory response. International Journal of Molecular Science. 2022, 23(19):11086. (IF=6.208, Q1/二区).
4. X Y Chen, Y J Lu, M Y Shan, H Y Zhao, Z X Lu*, Y J Lu*. A mini-review: mechanism of antimicrobial action and application of surfactin. World Journal of Microbiology and Biotechnology, 2022, 38(8): 143.(高被引,IF= 4.253, Q2/三区).
5. X Y Chen, H Y Zhao, F Q Meng, L B Zhou, X Y Pang, Z X Lu*, Y J Lu*. Ameliorated effects of a lipopeptide surfactin on insulin resistance in vitro and in vivo. Food Science & Nutrition, 2022,10(7): 2455-2469. (IF=3.553, Q2/三区).
6. X Y Chen, J M Huang, H Y Zhao, Y J Lu, F Q Meng, F X Lu*, Z X Lu, Y J Lu*. Faecal untargeted metabolomics analysis elucidates the antihyperglycaemic effect of surfactin in high-fat diet/streptozotocin-induced type 2 diabetic mice. Revista Brasileira de Farmacognosia, 2023, 1-13. (IF=2.464, Q3/三区).
7. H. Y. Zhao, X.Y. Chen, L. Zhang, F.Q. Meng, L.B. Zhou, X.Y. Pang, Z. X. Lu*, Y.J. Lu*. Ameliorative effect of Lacticaseibacillus rhamnosus Fmb14 from Chinese yogurt on hyperuricemia. Food Science and Human Wellness. 2023, 12 (4):1379-1390. (IF= 8.022,Q1/一区).
8. H. Y. Zhao, X.Y. Chen, L. Zhang, F.Q. Meng, L.B. Zhou, X.Y. Pang, Z. X. Lu*, Y.J. Lu*. Lacticaseibacillus rhamnosus Fmb14 prevents purine induced hyperuricemia and alleviate renal fibrosis through gut-kidney axis. Pharmacological research, 2022,182:106350. (IF=10.334,Q1/一区).
9. H Y Zhao, X Y Chen, L Zhang, C Tang, F Q Meng, L B Zhou, P Zhu, Z X Lu*, Y J Lu*. Ingestion of Lacticaseibacillus rhamnosus Fmb14 prevents depression-like behavior and brain neural activity via the microbiota-gut-brain axis in colitis mice. Food & Function. 2023, 14(4): 1909-1928.(IF=6.317,Q1/一区).
10. H Y Zhao, X Y Chen, L Zhang, F Q Meng, L B Zhou, Z X Lu*, Y J Lu*. Lacticaseibacillus rhamnosus Fmb14 ameliorates hyperuricemia-induced hepatocyte pyroptosis via NLRP3 inflammasome cascade inhibition. Food Science and Human Wellness. 2023. (IF=8.022,Q1/一区).
11. X Y Chen, LX Lu; X H Xiong, X Xiong, Y J Liu. Development of a real-time PCR assay for the identification and quantification of bovine ingredient in processed meat products. Scientific Reports. 2020.10(1). (IF= 4.996, Q2/三区).
12. F Q Meng; Y B Lyu, X Y Chen; F X Lu; H Z Zhao; Y J Lu; M W Zhao, Z X Lu. Maltose-enhanced exopolysaccharide synthesis of Lactiplantibacillus plantarum through CRP-like protein. Journal of Agricultural and food Chemistry 2023. (IF= 5.895,Q1/一区).