1.个人信息(Personals)
陈晓宇,女,Tel: 15996272892,Email:chenxiaoyu@njau.edu.cn
2.受教育经历 (Educational Experience)
2012.9-2016.6 安徽农业大学 食品科学与工程专业 工学学士
2016.9-2019.6 南京工业大学 食品科学专业 工学硕士
2019.9-2023.6 南京农业大学 食品科学与工程专业 工学博士
3.工作经历(Professional Experience)
2023.7-至今 河南大学,讲师,Journal of Future Foods青年编委。
4.研究兴趣(Research Interests)
(1)食药两用资源的活性成分提取、分离和鉴定。
(2)天然产物活性研究:天然活性成分的降血糖、减脂肪、抗炎等作用,以及其作用靶点和分子机制研究。
5.承担/参与项目情况
[1] 2025.01-2027.12,主持国家自然科学基金青年项目,32402093,基于ISOC1调控脂代谢的金针菇膳食纤维减脂分子机制研究,30万;
[2] 2023.08.16-2025.12.31,参与河南省重点研发专项项目,231111112100,植物源食品功能配料精准营养研发关键技术及应用,240万;
[3] 2020.01-2024.12,参与国家自然科学基金面上项目,32072182,瑞士乳杆菌素NX371广谱抗菌的分子机制研究,58万。
6.代表性论著(Publications)
期刊论文(Journal Articles)
1. J M Wang, L Guo, X T Hao, T H Li, D Q Liu, F Zhang, X Y Chen*, W Y Kang*. Nontargeted metabolomics combining with intestinal microbiota and hypolipidemia targets elucidates anti-hyperlipidemia effect of Sangju yinzha tea in hyperlipidemia rats. Food Bioscience. 2025, 65: 106012. (IF=4.8, Q1/一区Top)
2. X Y Chen, T H Li, S S Zhang, C Tang, W Y Kang*. Research progress on glucose-regulating mechanism of food-derived polysaccharides. Food Bioscience. 2025, 63:105679. (IF=4.8, Q1/一区Top)
3. S Y Wang, Y H Chu, J J Yuan, Y Q Li, Z H Liu, X Y Chen*, W Y Kang*. Application and prospects of proteomic technology in inflammation:a review. Food Science and Human Wellness. 2024, 13(05): 2373-2385. (IF=5.6, Q1/一区Top)
4. X Y Chen, H Y Zhao, Y J Lu, F Q Meng, Z X Lu*, Y J Lu*. Surfactin mitigates dextran sodium sulfate-induced colitis and behavioral disorders in mice by mediating gut-brain-axis balance. Journal of Agricultural and food Chemistry. 2023,71 (3): 1577-1592. (IF=5.895,Q1/一区Top).
5. X Y Chen, H Y Zhao, F Q Meng, L B Zhou, Z X Lu*, Y J Lu*. Surfactin alleviated hyperglycaemia in mice with type 2 diabetes induced by a high-fat diet and streptozotocin. Food Science and Human Wellness. 2023,12(6): 2095-2110. (IF=8.022,Q1/一区Top).
6. X Y Chen, H Y Zhao, Y J Lu, H W Liu, F Q Meng, Z X Lu*, Y J Lu*. Surfactin mitigates a high-fat diet and streptozotocin-induced type 2 diabetes through improving pancreatic dysfunction and inhibiting inflammatory response. International Journal of Molecular Science. 2022, 23(19):11086. (IF=6.208, Q1/二区).
7. X Y Chen, Y J Lu, M Y Shan, H Y Zhao, Z X Lu*, Y J Lu*. A mini-review: mechanism of antimicrobial action and application of surfactin. World Journal of Microbiology and Biotechnology, 2022, 38(8): 143.(高被引,IF= 4.253, Q2/三区).
8. X Y Chen, H Y Zhao, F Q Meng, L B Zhou, X Y Pang, Z X Lu*, Y J Lu*. Ameliorated effects of a lipopeptide surfactin on insulin resistance in vitro and in vivo. Food Science & Nutrition, 2022,10(7): 2455-2469. (IF=3.553, Q2/三区).
9. X Y Chen, J M Huang, H Y Zhao, Y J Lu, F Q Meng, F X Lu*, Z X Lu, Y J Lu*. Faecal untargeted metabolomics analysis elucidates the antihyperglycaemic effect of surfactin in high-fat diet/streptozotocin-induced type 2 diabetic mice. Revista Brasileira de Farmacognosia, 2023, 1-13. (IF=2.464, Q3/三区).
10. X Y Chen, LX Lu, X H Xiong, X Xiong, Y J Liu. Development of a real-time PCR assay for the identification and quantification of bovine ingredient in processed meat products. Scientific Reports. 2020.10(1). (IF= 4.996, Q2/三区).
11. J G Xu, X Q Sun, Y Qian, S Y Jia, Q Zhang, C Tang, J Kan, J Liu, X Y Chen. Research progress on cancer-promoting mechanisms of high-fat diet. Food Science and Human Wellness. 2026, 15. (IF=5.6, Q1/一区TOP)
12. L Wang, Y X Chen, X J Meng, H Y Liang, Y D Zhang, H H Zhou, Y H Liu, X Y Chen, Z H Liu, S M Li, W Y Kang. Effects of undescribed iridoids in Patrinia punctiflora on insulin resistance in HepG2 cells. Fitoterapia, 2024, 178, 106160. (IF=2.5, Q3/三区)
13. D X Sun-Waterhouse, X YChen, Z H Liu, G I.N. Waterhouse, W Y Kang. Transformation from traditional medicine-food homology to modern food-medicine homology. Food & Medicine Homology. 2024, 1(1): 9420014.
14. H. Y. Zhao, X.Y. Chen, L. Zhang, F.Q. Meng, L.B. Zhou, X.Y. Pang, Z. X. Lu*, Y.J. Lu*. Ameliorative effect of Lacticaseibacillus rhamnosus Fmb14 from Chinese yogurt on hyperuricemia. Food Science and Human Wellness. 2023, 12 (4):1379-1390. (IF= 8.022,Q1/一区Top).
15. H Y Zhao, X Y Chen, L Zhang, C Tang, F Q Meng, L B Zhou, P Zhu, Z X Lu*, Y J Lu*. Ingestion of Lacticaseibacillus rhamnosus Fmb14 prevents depression-like behavior and brain neural activity via the microbiota-gut-brain axis in colitis mice. Food & Function. 2023, 14(4): 1909-1928.(IF=6.317,Q1/一区Top).
16. H Y Zhao, X Y Chen, L Zhang, F Q Meng, L B Zhou, Z X Lu*, Y J Lu*. Lacticaseibacillus rhamnosus Fmb14 ameliorates hyperuricemia-induced hepatocyte pyroptosis via NLRP3 inflammasome cascade inhibition. Food Science and Human Wellness. 2023. (IF=8.022,Q1/一区Top).
17. H. Y. Zhao, X.Y. Chen, L. Zhang, F.Q. Meng, L.B. Zhou, X.Y. Pang, Z. X. Lu*, Y.J. Lu*. Lacticaseibacillus rhamnosus Fmb14 prevents purine induced hyperuricemia and alleviate renal fibrosis through gut-kidney axis. Pharmacological research, 2022,182:106350. (IF=10.334,Q1/一区Top).
18. F Q Meng, Y B Lyu, X Y Chen, F X Lu, H Z Zhao, Y J Lu, M W Zhao, Z X Lu. Maltose-enhanced exopolysaccharide synthesis of Lactiplantibacillus plantarum through CRP-like protein. Journal of Agricultural and food Chemistry 2023. (IF= 5.895,Q1/一区Top).
7.论著(books):
专著《Bio-based antimicrobial agents to improve agricultural and Food safety》Chapter1-Surfactin biosynthesis and its potential applications in agriculture and food system. By X Y Chen, H W Liu, Z X Lu. Bentham Science Publishers. 2024. ISBN: 978-981-5256-24-6.